Ryan Henderson was a Central Intelligence Agency special agent. He served in only one mission known as Uprise.
After presumably killing and destroying all zombies and evidence at Crisis, Alex Mason, Frank Woods, Joseph Bowman, and Jason Hudson return to the US. They are forced into the witness protection program to protect their identities and are forced to forever live at the Pentagon. All seemed well. However, during one rainy day in April, an urgent message is relayed to the Pentagon. The message requested immediate assistance, but the sender was unknown. The CIA tracked the signal to the coordinates, which led to an old Soviet experimentation laboratory in South America. Mason, Woods, Bowman, and Swift are organized into a task force and flown to the location. They parachute out of the plane. Also instantly the four are attacked by zombies. While trying to reach the escape boat, several zombies pull Swift under, presumably drowning him. The other three return to the Pentagon and report what happened. The CIA sent a scout force to the facility to investigate (consisting of Ryan Jackson, Richard Kain, Daniel Fulsang, and Devon Pangburn), but none of them returned.